When there is not sufficient oxygen delivered to the muscles of the legs, pain may occur during exercise. This most commonly occurs because there is insufficient blood delivered to the legs The disorder is more common in men and usually occurs after 40 years of age. Certain risk factors, such as smoking, hypertension and a high fat diet, may increase the risk of developing ischemic claudication.
Causes of Ischemic Claudication
The primary cause of ischemic claudication is atherosclerosis. Here, disease in the arterial wall leads to narrowing of the arteries. Smoking is a major contributing factor as is diabetes. There are conditions which are inherited, such as hypercholesterolemia or hyperlipidemia, that may accelerate the progression of atherosclerosis. Embolization of a blood clot from the heart may lead to rapid or complete obstruction of an artery of the leg. Emboli from the diseased arteries, themselves, may further obstruct smaller vessels.
Signs and Symptoms of Ischemic Claudication
The onset of symptoms develops over months or years. Initially, one leg may be involved. They typical symptoms of ischemic claudication include pain in one or both calves when walking. The ability to walk is limited to about the same distance each time. Rest usually allows the pain to resolve within several minutes. Other features of ischemic disease of the leg include pale, cold feet. Sometimes, ulcerations of the legs may develop that do not readily heal. Pain in the buttocks may occur and men may experience problems with erections.
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Medical Content Last Updated on 07/12/2008
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