Myoglobinuria

Overview of Myoglobinuria

Myoglobin is the red pigment in the muscle that is responsible for its color. When the muscle cells are damaged, from any cause, some of the myoglobin is liberated from the cells into the blood stream. They are collected in the kidneys, where they lead to discoloration of the urine. The myoglobin may damage the kidney leading to renal failure when it is severe.

Causes of Myoglobinuria

Paroxysmal myoglobinuria may produce this and is unknown cause. Crush injury to the muscles or surgical damage to the muscles can lead to myoglobinuria. Stupor or coma which produces pressure injury to a muscle can lead to this disorder. Prolonged seizures can lead to disruption of the muscle.

Signs and Symptoms of Myoglobinuria

The urine appears dark or burgundy. There is pain and tenderness in the affected muscles. There may be weakness of the damaged muscles. Renal failure may lead to decreased urine output and weight gain.

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Medical Content Last Updated on 07/12/2008

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