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Stevens-johnson Syndrome


Overview of Stevens-johnson Syndrome

overview

Stevens-Johnson syndrome represents an adverse skin reaction to certain drugs. It is rare, probably accounting for less than 1% of skin reactions from drugs. It is a blistering abnormality. It is similar to Erythema multiforme, but is usually more severe. It is also similar to Toxic epidermal necrolysis, but usually not as severe as this disease. Less than ten percent of the surface of the body is usually affected. It often produces red-purple lesions of the skin and mucus membranes.

Causes of Stevens-johnson Syndrome

causes

This disorder is often seen in response to drug reactions. The exact cause is somewhat uncertain.

Signs and Symptoms of Stevens-johnson Syndrome

signs and symptoms

Red-purple lesions develop diffusely on the body, mouth, anus, genitals, GI tract and skin. They usually do not involve more than 10% of the total body surface area. Commonly, fever and generalized weakness occur.


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Medical Content Last Updated on 07/12/2008

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