Ankylosing spondylitis is an inflammatory arthritis. It primarily affects the joints of the trunk.. These include primarily the back and neck. In addition, the hips, shoulders and ribs may be involved. Pain and stiffness are early signs. Most cases are relatively mild. However, advanced cases have rigid spines. Over half of those that develop this disorder have a family history of the disease. Males are affected far more often than females. The onset is during the second and third decade of life. People who suffer from this disorder may also have Crohn's disease or Ulcerative colitis.
Causes of Spondylitis, Ankylosing
The cause of ankylosing spondylitis is unknown. It may be caused by genetic changes or autoimmune disorder.
Signs and Symptoms of Spondylitis, Ankylosing
Most cases, especially early on, only have back or neck pain and stiffness. These episodes tend to be recurrent. As the disease progresses, increasing stiffness of the spine is noted. There is increased pain. The joints of the arms and legs, especially the shoulders and hips, may become stiff, painful and with a decrease range of motion. Muscle stiffness, fatigue, weight loss and inflammation of the iris (colored part of the eye) may occur.
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Medical Content Last Updated on 07/12/2008
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