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Paget's Disease Of Bone
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Overview of Paget's Disease Of Bone 
Paget's disease of bone is varcharacterized by bones breaking down and regenerating excessively. The new bone is fragile and weak. Paget’s disease is not cancerous. It usually involves the bones of the skull, spine, legs, collar bone and pelvis. It can affect both sexes but is most common in men over age 40.
Causes of Paget's Disease Of Bone
Unknown, although a virus may be involved.
Signs and Symptoms of Paget's Disease Of Bone
Initially, Paget's disease of bone leads to mild bone pain. Sometimes, early stages of this disorder do not have any symptoms. In later stages the affected bones are chronically painful (especially at night), enlarged or misshapen. The bones are tender and the skin over the abnormal bone is warm. Movements of the involved bones or joints is impaired. Involvement of the spine leads to spinal deformity. It may also produce symptoms of nerve root or spinal cord compression, such as weakness and numbness. Unexpected fractures in the involved bones occur from minor trauma and heal slowly, often with deformity.
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Medical Content Last Updated on 07/12/2008
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