Immunodeficiency diseases are varcharacterized by defects in the body’s immune system. In a healthy immune system, the body is protected against germs (bacteria, viruses and fungi), cancer and any foreign material that enters the body. The body becomes susceptible to infection and cancer, when this system is defected. It can occur in all ages and sexes. Other forms of this disease are acquired immunodeficiency syndrome (AIDS), and the immunosuppression some people develop due to potent drugs used to treat several disorders.
Causes of Immunodeficiency Diseases
Immunodeficiency diseases can occur from congenital defects that involve an incomplete or absent immune system. The surgical removal of the spleen before age 2 may affect the eventual development and function of the immune system. Use of immunosuppressive drugs, radiation treatment, some cancers, such as Hodgkin’s disease, hypogammaglobulinemia, and viral infections can all lead to compromise of the immune system.
Signs and Symptoms of Immunodeficiency Diseases
The symptoms that occur with immunodeficiency diseases include recurrent and unusual infections. The infections that do develop may be more severe than normal. Unusual infections, particularly those caused by fungi or tuberculosis can develop. Certain forms of cancer are more prevalent, particularly leukemia. Bleeding disorders, eczema, meningitis and encephalitis may occur with an increased frequency.
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Medical Content Last Updated on 07/12/2008
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