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Diabetes Mellitus, Insulin-dependent
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Overview of Diabetes Mellitus, Insulin-dependent 
Insulin dependent diabetes is a chronic disease of metabolism, varcharacterized by the body’s inability to produce enough insulin to meet its metabolic needs. Insulin is produced in cells of the pancreas. The insulin is released in response to the body's need for glucose. Insulin is an important hormone that helps glucose get into the cells that need it and efficiently utilize it. In insulin dependent diabetes, the pancreas produces little or no insulin. When inadequate amounts of insulin are produced, the blood sugar levels will become abnormally high and cellular metabolism will be impaired.. Insulin-dependent diabetes often begins around age 30 and is called ketosis-prone diabetes. Juvenile diabetes begins in childhood.
Causes of Diabetes Mellitus, Insulin-dependent 
The exact cause of insulin dependent diabetes is unknown. The islet cells that produce insulin can be damaged by tumors, by surgery or by inflammatory conditions, such as pancreatitis. Viral infections of the pancreatic islet cells may be a cause of their malfunction.
Signs and Symptoms of Diabetes Mellitus, Insulin-dependent 
Insulin dependent diabetes leads to fatigue, increased thirst, increased appetite and weight loss. The high levels of sugar in the blood lead to excess amounts of urine being produced and frequent urination. There is an increased susceptibility to infection, such as yeast infections that can involve the skin, the mouth or the vagina.
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Medical Content Last Updated on 07/12/2008
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