Crohn's Disease

Overview of Crohn's Disease

Crohn's disease is a recurrent inflammatory disease affecting the gastrointestinal tract. Sections of the intestinal tract which may be affected include the ileum, the lower part of the small intestine and the colon, or large intestine. The lymph nodes that drain these areas and their attachments to the body wall through the mesentery may also be involved. Caucasians are affected more often, usually between the ages of 15 and 35. There may be some hereditary component of this disorder.

Causes of Crohn's Disease

The cause of Crohn's disease is unknown. Hereditary or environmental factors may be important.

Signs and Symptoms of Crohn's Disease

The symptoms of Crohn's disease include recurrent diarrhea, that may be bloody. Abdominal pain or cramping occurs. This is most common in the umbilical area or on the right side of the abdomen. However, the location of the pain can vary depending on what portion of the intestinal tract is involved. There may be loss of weight and loss of appetite. The pain may worsen after eating. Fatigue and general ill feeling may be noted. Joint pain and skin rashes may develop as well.

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Medical Content Last Updated on 07/12/2008

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