Buerger's Disease

Overview of Buerger's Disease

Buerger's disease is caused by inflammation of the small and medium arteries. This leads to temporary blockage of these blood vessels, often in response to nicotine. This can result in clot formation. The arteries usually affected are ones in the legs and feet. Cigarette smoking is a significant factor in developing this disease and its occurrence is extremely rare among non-smokers. It is commonly seen in cigarette-smoking men between ages 20 and 40.

Causes of Buerger's Disease

Buerger's disease is caused by temporary obstruction of the essential blood vessels in the extremities in response to blood vessel spasm. Cigarette smoking and nicotine trigger this spasm.

Signs and Symptoms of Buerger's Disease

Symptoms of Buerger's disease are the result of insufficient blood supply. They include intermittent pain during exercise. This localized pain in the lower extremities improves with rest. Other symptoms include: blueness, heat and tingling in the legs when exposed to cold, painful ulcers on the toes and occasionally in the fingertips.

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Medical Content Last Updated on 07/12/2008

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