Benign pigmented lesions affecting the skin are largely grouped into one of three areas. These include Pigmented moles, Congenital nevi and Acquired nevi. The Pigmented moles occur at birth. The Congenital nevi develop in about 1 to 2.5 % of newborns. Gradually they may change from flat, pale pigmented lesion to an elevated, verrucous, hair lesion. Lastly, acquired nevi are extremely common. They appear about eight month of the life and increase in number with age, apparently reaching their peak numerically in the late third decade of life. Thereafter, the number of nevi begin to decrease as one ages, so that elderly persons average far fewer nevi than younger adults.
Causes of Pigmented Verrucous Nevi
The term "nevus" by itself implies faulty development. We usually think of moles as "nevi" and they in fact do represent one form of nevus, in which a modified form of melanocyte proliferates to form a kind of benign tumor. Nevus cells of melanocytic origin migrate to the skin from the neural crest during embryonic life. They typically aggregate along the dermal-epidermal junction, forming junctional nevi, and later "drop off" into the dermis, forming compound nevi and ultimately (when no more nevus cells remain at the junction), intradermal nevi. If left alone and the individual lives long enough, nevi are thought to eventually disappear.
Signs and Symptoms of Pigmented Verrucous Nevi
These pigmented lesions are small, usually slightly raised with an irregular or rough surface.
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Medical Content Last Updated on 07/12/2008
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